Prognostic significance of tryptophan catabolism in adult T-cell leukemia/lymphoma Short title: Tryptophan catabolism in ATL Authors:
نویسندگان
چکیده
Institutions: Department of Hematology & Oncology, Nagoya City University Graduate School of Medical Sciences, Department of Anatomic Pathology and Molecular Diagnostics, Nagoya City University Graduate School of Medical Sciences, Laboratory of Hospital Pharmacy, Nagoya City University Graduate School of Pharmaceutical Sciences,Department of Tumor Immunology, Aichi Medical University School of Medicine, Department of Hematology and Oncology, Nagoya City West Medical Center, Department of Respiratory Medicine, Allergy and Rheumatology, Nagoya City University Graduate School of Medical Sciences, Department of Hematology, Imamura Bun-in Hospital
منابع مشابه
Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma.
PURPOSE Indoleamine 2,3-dioxygenase 1 (IDO1: IDO), an enzyme catabolizing tryptophan (Trp) into the kynurenine (Kyn) pathway, is increasingly being recognized as an important microenvironmental factor suppressing antitumor immune responses. The purpose of the present study was to determine the prognostic significance of Trp catabolism in adult T-cell leukemia/lymphoma (ATL). EXPERIMENTAL DESI...
متن کاملBiology of Human Tumors Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma
Purpose: Indoleamine 2,3-dioxygenase 1 (IDO1: IDO), an enzyme catabolizing tryptophan (Trp) into the kynurenine (Kyn) pathway, is increasingly being recognized as an important microenvironmental factor suppressing antitumor immune responses. The purpose of the present study was to determine the prognostic significance of Trp catabolism in adult T-cell leukemia/lymphoma (ATL). Experimental Desig...
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Indoleamine 2,3-dioxygenase 1 (IDO) is an enzyme catabolizing tryptophan (Trp) into the kynurenine (Kyn) pathway. The purpose of the present study was to determine the clinical significance of Trp catabolism in newly diagnosed Hodgkin lymphoma (HL) patients. We quantified serum Trp and Kyn in 52 HL patients, and analyzed their associations with different clinical parameters including serum solu...
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